La Grande CrèmeLa Grande Crme is the fruit of years of research and development. To develop this pioneering formulation, Biologique Recherche identified and selected EpigenActiv, a peptide that acts on Epidermal Growth Factor (EGF) receptors, essential to regenerate tissues and recycle degraded proteins. With a number of carefully selected active ingredients, La Grande Crme does not just reverse DNA damage and rejuvenate cells but also prevents cutaneous aging,

this cream is rich in apple extract which strengthens the skin barrier functions

and types IV and VII to improve the appearance of the dermal-epidermal junction

A concentrated Tocopherol Complex (a potent form of Vitamin E) helps skin to retain moisture and offers a hydrated

The ultimate solution for sensitive skin

there’s a true sensation of comfort

Is naturally found in sugar cane

A symphony of five powerful peptides target specific cellular functions and rejuvenate fibroblast cells

Not a desire to return —

Perfect For

The cold sensation is picked up by receptors in the skin

and soothing at-home spa ritual

Our Night Complex is a powerful concentrate of actives designed to gently heal the skin from daily aggressions